Barton Kamen, MD, PhD

Barton Kamen, MD, PhD

The Cancer Institute of New Jersey
195 Little Albany Street
New Brunswick, NJ 08903
Phone: (732) 235-5437
Fax: (732) 235-8234

Dr. Kamen specializes in Pediatric Hematology/Oncology.

Medical School
  • Case Western Reserve University School of Medicine, Cleveland, OH
Internship
  • Yale University School of Medicine, New Haven, CT
Residency
  • Yale University School of Medicine, New Haven, CT
Fellowship
  • Yale University School of Medicine, New Haven, CT
Board Certification
  • Pediatric Hematology-Oncology, American Board of Pediatrics
  • American Board of Pediatrics
Publications
  • Cole, PD, Gorlick R, Banerjee D, Tong WP, Smith A, Kamen BA, Bertino JR: Effects of overexpression of gamma-glutamyl hydrolase on methotrexate metabolism and resistance. Cancer Research 61:4599-4604, 2001.
  • Mantadakis E, Smith AK, Hyman L, Winick NJ and Kamen BA: Methotrexate polyglutamation may lack prognostic significance in children with B-lineage acute lymphoblastic leukemia treated with intensive oral methotrexate with minimal leucovorin rescue. J Ped Hem Oncol 24:636-642, 2002.
  • Cole PD, Smith AK, Kamen BA: Nucleoside Salvage Contributes to Methotrexate Resistance in Osteosarcoma Cell Lines, but Confers Collateral Sensitivity to Nucleoside Analogs. Cancer Chemother and Pharmacol 50:111-116, 2002.
  • Kerbel RS, Klement G, Pritchard KI and Kamen B. Continuous Low Dose Anti-Angiogenic/Metronomic Chemotherapy: From the Research Laboratory into the Oncology Clinic. Annals of Oncology 13:12-15, 2002.
  • Drachtman R, Cole PD, Golden CB, James SJ, Melynk S, Smith AK, Asiner J, Kamen BA: Dextromethorphan is effective in the treatment of subacute methotrexate toxicity. Ped Hem Onc 19:319-327, 2002.
  • Winter-Vann AM, Kamen BA, Bergo MO, Young SG, Melnyk S, James SJ and Casey PJ: Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate. Proc Nat Acad Sci 100:6529-6534, 2003.
  • Kaufman Y, Drori S, Cole PD, Kamen BA, Sirota J, Ifergan I, Weyl Ben Arush M, Elhasid R, Sahar D, Kaspers GJL, Jansen G, Matherly LH, Rechavi G, Toren A, Assaraf YG: Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia. Cancer 100: 773-782, 2004.
  • Kamen BA, Smith AK: A review of folate receptor alpha cycling and 5-methyltetra-hydrofolate accumulation with an emphasis on cell models in vitro. Adv Drug Deliv Rev. 56:1085-97. 2004.
Gender
  • Male